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In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside.

机译：在纤维素检测β-氨基己糖苷酶a亚基的β-α杂合构建体中，据报道与Gm2激活蛋白相互作用并水解Gm2神经节苷脂。

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Incilay Sinici; Sayuri Yonekawa; Ilona Tkachyova; Steven J Gray; R Jude Samulski; Warren Wakarchuk; Brian L Mark; Don J Mahuran;
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年度 2013
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1. Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human beta-hexosaminidase A on the accumulated GM2 ganglioside. [J] . Ohsawa M, Kotani M, Tajima Y, Journal of human genetics . 2005,第9期

机译：Sandhoff小鼠永生化的Schwann细胞的建立以及重组人β-己糖胺酶A对积累的GM2神经节苷脂的纠正作用。
2. A single site in human beta-hexosaminidase A binds both 6-sulfate-groups on hexosamines and the sialic acid moiety of GM2 ganglioside. [J] . Sharma R, Bukovac S, Callahan J, Biochimica et biophysica acta: international journal of biochemistry and biophysics . 2003,第1期

机译：人β-己糖胺酶A中的单个位点结合了己糖胺上的6-硫酸盐基团和GM2神经节苷脂的唾液酸部分。
3. In silico mutational study reveal improved interaction between Beta-Hexosaminidase A and GM2 activator essential for the breakdown of GM2 and GA2 Gangliosides on Tay-Sachs disease [J] . Kritika Kapruwan, Rahul Parida, Rajiniraja Muniyan Research journal of pharmacy and technology . 2017,第11期

机译：在基石突变研究中，揭示了β-己糖胺酶A和GM2活化剂之间的改善的相互作用，对于Tay-Sachs病的GM2和Ga2神经节苷脂的崩溃是必需的
4. Biophysical characterization of the GM2 activator protein by site directed spin labeling electron paramagnetic resonance spectroscopy. [D] . Mathias, Jordan Delyn. 2009

机译：GM2激活蛋白的定点自旋标记电子顺磁共振光谱的生物物理表征。
5. In Cellulo Examination of a Beta-Alpha Hybrid Construct of Beta-Hexosaminidase A Subunits Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside [O] . Incilay Sinici, Sayuri Yonekawa, Ilona Tkachyova, -1

机译：在测试版 - 氨基己糖苷酶α亚基的β-α杂构建的纤维素的检验报告进行互动与Gm2活化因子蛋白质并水解Gm2神经节苷脂
6. Construction of a hybrid β-hexosaminidase subunit capable of forming stable homodimers that hydrolyze GM2 ganglioside in vivo [O] . Michael B Tropak, Sayuri Yonekawa, Subha Karumuthil-Melethil, 2016

机译：构建能够形成体内水解Gm2神经节苷脂的稳定同型二聚体的杂合β-氨基己糖苷酶亚基的构建

In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside.

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